Distribution of phage-associated virulence genes in pharyngeal group a streptococcal strains isolated in Italy.
نویسندگان
چکیده
The presence and assortment of 16 known virulence/resistance genetic determinants carried by prophages or prophage-like elements were tested in 212 clinical group A Streptococcus (GAS) strains and related to available data from SmaI macrorestriction/pulsed-field gel electrophoresis analysis and emm typing. A strong correlation existed among the three analyses. This finding supports the substantial contribution to the evolution and diversification of the GAS genome attributed to phages.
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 47 5 شماره
صفحات -
تاریخ انتشار 2009